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EIF2S3 (eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa) Blocking Peptide (100ug)

EIF2S3 (eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa) Blocking Peptide (100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-EIF2S3 antibody (Catalogue #: ARP46057_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Presku: AAP46057
Size: 100 ug
Weight: 51kDa
Gene: 1968
Format: Lyophilized powder
Target: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.
Alternative names: EIF2; EIF2G; EIF2gamma
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