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EIF2B1 Human - Recombinant Human Eukaryotic Translation Initiation Factor 2B Subunit 1 Alpha (1ug)

EIF2B1 Human - Recombinant Human Eukaryotic Translation Initiation Factor 2B Subunit 1 Alpha (1ug)

Product Introduction: EIF2B1 is one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), which is a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Phosphorylation of eIF2 inhibits GEF activity of EIF2B, an inhibition which requires the eIF2B1 subunit. Defects in eIF2B1 are a cause of leukoencephalopathy with vanishing white matter (VWM), a brain disease which is characterized by head trauma and motor deterioration.
Product Description: EIF2B1 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 325 amino acids (1-305 a.a.) and having a molecular mass of 35.8kDa. EIF2B1 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

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SPECIFICATIONS

Size

1ug

Format

Sterile Filtered colorless solution.

Presku

OPPA00114

Alternative Names

Translation initiation factor eIF-2B subunit alpha; eIF-2B GDP-GTP exchange factor subunit alpha; EIF2B1; EIF2BA; EIF2B.

SUPPLIER INFO

Aviva Systems Biology Incorporated

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