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EIF2AK3 (5G5) Antibody

EIF2AK3 (5G5) Antibody

Cat no: 253074

Supplier: ABBIOTEC
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EIF2AK3 (Eukaryotic translation initiation factor 2-alpha kinase 3; PERK) is a Ser/Thr protein kinase. It phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation and to a rapid reduction of translational initiation and repression of global protein synthesis. PERK serves as a critical effector of unfolded protein response (UPR)-induced G1 growth arrest due to the loss of cyclin D1. Defects in PERK are the cause of Wolcott-Rallison syndrome, an early-onset diabetes mellitus.
Catalogue number: 253074
Reactivities: Human
Applications: Western Blot
Size: 0.1 ml
Accession: Q9NZJ5, NP_004827
Antigen: Purified recombinant fragment of human EIF2AK3 e, Xenopus/Amphibian,pressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
P type: Mouse Monoclonal Antibody
Isotype: Mouse IgG1
Clonality: 5G5
Additional info: Eukaryotic translation initiation factor 2-alpha kinase 3; PRKR-like endoplasmic reticulum kinase; Pancreatic eIF2-alpha kinase; HsPEK; EIF2AK3; PEK; PERK
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