EhpB1 (EPH receptor B1) is a receptor for ephrin-B family members. Ephrin receptors and their ligands, the ephrins,Mouse,edate numerous developmental processes,Porcinearticularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their e, Xenopus/Amphibian,tracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family.