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EGFR Antibody

EGFR Antibody

Cat no: 250631


Supplier: ABBIOTEC
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Epidermal growth factor receptor (EGFR) is a receptor for EGF and for various members of the EGF family such as TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. EGFR is involved in the control of cell growth and differentation. Binding of EGF to the receptor leads to dimerization, internalization of the EGF-receptor comple, Xenopus/Amphibian,, induction of the tyrosine kinase activity, stimulation of cell DNA synthesis and cell proliferation. Defects in EGFR are associated with lung cancer.
Catalogue number: 250631
Reactivities: Human, Mouse, Rabbit
Applications: Immunohistochemistry
Size: 0.1 mg
Accession: P00533
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human EGFR.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type: Rabbit Polyclonal Antibody
Isotype: Rabbit Ig
Additional info: Epidermal growth factor receptor; receptor tyrosine-protein kinase ErbB-1; EGFR; ERBB1