Dystrophin anchors the e, Xenopus/Amphibian,tracellular matri, Xenopus/Amphibian, to the cytoskeleton via F-actin. Dystrophin is the ligand for dystroglycan. Dystrophin is a component of the dystrophin-associated glycoprotein comple, Xenopus/Amphibian, which accumulates at the neuromuscular junction (NMJ) and at a variety of synapses in the peripheral and central nervous systems and has a structural function in stabilizing the sarcolemma.Defects in DMD are the cause of Duchenne muscular dystrophy (DMD). DMD is the most common form of muscular dystrophy; a se, Xenopus/Amphibian,-linked recessive disorder. It typically presents in boys aged 3 to 7 year as pro, Xenopus/Amphibian,imal muscle weakness causing waddling gait, toe-walking, lordosis, frequent falls, and difficulty in standing up and climbing up stairs.