Reactivities: | Human |
Presku: | AAP51954 |
Size: | 100ug |
Weight: | 71kDa |
Gene: | 1781 |
Format: | Lyophilized powder |
Target: | DYNC1I2 acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCNT1. Involved in membrane-transport, such as Golgi apparatus, late endosomes and lysosomes. |
Alternative names: | DNCI2; FLJ21089; FLJ90842; IC2; MGC104199; MGC111094; MGC9324 |