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DVL1 (Human) cDNA (1ug)

DVL1 (Human) cDNA (1ug)

Supplier: Aviva Systems Biology Incorporated
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The ORF of human DVL1 is amplified by PCR using a high fidelity enzyme and sub-cloned into a Prokaryotic expression vector under the control of the tac promoter. The expression of the gene has been confirmed by Western blot using an anti-DVL1 polyclonal antibody.
Presku: ANA11070
Size: 1ug
Gene: 1855
Target: DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development.
Alternative names: DVL; DVL1L1; MGC54245
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