Reactivities: | Human |
Presku: | AAP69725 |
Size: | 100ug |
Weight: | 36kDa |
Gene: | 374946 |
Format: | Lyophilized powder |
Target: | DRAXIN is a chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. It acts as a chemorepulsive guidance protein for commissural axons during development and is able to inhibit or repel neurite outgrowth from dorsal spinal cord. DRAXIN inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. |
Alternative names: | AGPA3119; UNQ3119; neucrin |