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DR3/TRAMP Antibody

DR3/TRAMP Antibody

Cat no: 250889


Supplier: ABBIOTEC
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Tumor necrosis factor receptor superfamily member 25 (TRAMP/DR3 or Apoptosis-mediating receptor DR3) is the receptor for TNFSF12/APO3L/TWEAK. TRAMP interacts directly with the adapter TRADD. TRAMP mediates activatio of NFkB and induces apoptosis. TRAMP/DR3 plays a role in regulating lymphocyte homeostasis. TRAMP/DR3 forms homodimers to interact strongly via the death domains with TNFRSF1 and TRADD to activate the apoptosis and NFkB signaling cascades. DR3 is highly e, Xenopus/Amphibian,pressed in thymocytes and lymphocytes.
Catalogue number: 250889
Reactivities: Human, Mouse, Rabbit
Applications: Immunohistochemistry
Size: 0.1 mg
Accession: Q93038
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N/C-term region of human TRAMP/DR3.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type: Rabbit Polyclonal Antibody
Isotype: Rabbit Ig
Additional info: Tumor necrosis factor receptor superfamily member 25; WSL-1 protein; Apoptosis-mediating receptor DR3; Apoptosis-mediating receptor TRAMP; Death domain receptor 3; WSL protein; Apoptosis-inducing receptor AIR; Apo-3; Lymphocyte-associated receptor of death; LARD; TNFRSF25; APO3; DDR3; DR3; TNFRSF12; WSL; WSL1