

Supplier:
Aviva Systems Biology IncorporatedDOK2 (docking protein 2, 56kDa) Blocking Peptide (100ug)
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SPECIFICATIONS
Size
100 ug
Format
Lyophilized powder
Presku
AAP30360
Target
DOK2 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210 (bcr/abl), a chimeric protein whose presence is associated with CML. DOK2 binds p120 (RasGAP) from CML cells.The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells.
Weight
45kDa
Gene Id
9046
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