A number of serum proteins participate in acute inflammatory reactions. These include the complement, coagulation and kinin systems as well as a number of other proteins, known as acute phase proteins, that regulate acute inflammation.
The complement system is a complex set of up to 20 serum proteins. The most abundant and pivotal of the complement components is C3, which has a molecular weight of about 187 kD and consists of an alpha and beta chain.
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