Presku: | AAP52138 |
Size: | 100 ug |
Weight: | 52kDa |
Gene: | 10395 |
Format: | Lyophilized powder |
Target: | This gene is deleted in the primary tumor of hepatocellular carcinoma. It maps to 8p22-p21.3, a region frequently deleted in solid tumors. It is suggested that this gene is a candidate tumor suppressor gene for human liver cancer, as well as for prostate, lung, colorectal, and breast cancers. DLC1 functions as a GTPase-activating protein specific for Rho and an activator of PLCD1 in vivo and induces morphological changes and detachment through cytoskeletal reorganization. |
Alternative names: | ARHGAP7, FLJ21120, HP, STARD12, p122-RhoGAP |