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Dkk4 (dickkopf homolog 4 (Xenopus laevis) ) Blocking Peptide (the C terminal of Dkk4)(100ug)

Dkk4 (dickkopf homolog 4 (Xenopus laevis) ) Blocking Peptide (the C terminal of Dkk4)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-Dkk4 Antibody (ARP42406_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human, Mouse
Presku: AAP42406
Size: 100ug
Weight: 24kDa
Gene: 234130
Format: Lyophilized powder
Target: Dkk4 antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.
Alternative names: Dkk-4; MGC25705
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