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DGCR2 (Human) cDNA (1ug)

DGCR2 (Human) cDNA (1ug)

Supplier: Aviva Systems Biology Incorporated
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The ORF of human DGCR2 is amplified by PCR using a high fidelity enzyme and sub-cloned into a Prokaryotic expression vector under the control of the tac promoter. The expression of the gene has been confirmed by Western blot using an anti-DGCR2 polyclonal antibody.
Presku: ANA11391
Size: 1ug
Gene: 9993
Target: Deletions of the 22q11.2 have been associated with a wide range of developmental defects (notably DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome and isolated conotruncal cardiac defects) classified under the acronym CATCH 22. The DGCR2 gene encodes a novel putative adhesion receptor protein, which could play a role in neural crest cells migration, a process which has been proposed to be altered in DiGeorge syndrome. Alternative splicing results in multiple transcript variants.
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