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Desmin Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 251743

Desmin Antibody

Desmin is a class-III intermediate filament found in muscle cells. In adult striated muscle desmin forms a fibrous network connecting myofibrils to each other and to the plasma membrane from the periphery of the Z-line structures. Defects in desmin are the cause of myopathy myofibrillar desmin-related (MFM-DES), also known as desmin-related myopathy (DRM). DRM is a neuromuscular disorder characterized by skeletal muscle weakness associated with cardiac conduction blocks, arrhythmias, restrictive heart failure, and by myofibrillar destruction with intracytoplasmic accumulation of desmin-reactive deposits in cardiac and skeletal muscle cells.

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SPECIFICATIONS

Catalog Number

251743

Size

0.1 mg

Applications

IHC

Reactivities

Hum, Mouse, Prc, Rabbit

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 2% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

P Type

Mouse Monoclonal Antibody

Antigen

Desmin from pig stomach.

Isotype

Mouse IgG1

Accession

P17661

Clonality

DES-82

Additional Info

DES; Desmin

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