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DDB2 (damage-specific DNA binding protein 2, 48kDa) Blocking Peptide (the C terminal of DDB2)(100ug)

DDB2 (damage-specific DNA binding protein 2, 48kDa) Blocking Peptide (the C terminal of DDB2)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-DDB2 Antibody (ARP60163_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP60163
Size: 100ug
Weight: 48kDa
Gene: 1643
Format: Lyophilized powder
Target: This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities.
Alternative names: DDBB; FLJ34321; UV-DDB2
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