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DCP2 Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 252209

DCP2 Antibody

mRNA-decapping enzyme 2 (DCP2) is necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. DCP2 plays a role in replication-dependent histone mRNA degradation. DCP2 removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. DCP2 has higher activity towards mRNAs that lack a poly(A) tail, and has no activity towards a cap structure lacking a RNA moiety.

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SPECIFICATIONS

Catalog Number

252209

Size

0.1 mg

Applications

IHC

Reactivities

Hum, Mouse, Rabbit

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 2% BSA with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography.

P Type

Rabbit Polyclonal Antibody

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human DCP2.

Isotype

Rabbit Ig

Accession

Q8IU60

Additional Info

mRNA-decapping enzyme 2; hDpc; Nucleoside diphosphate-linked moiety , Xenopus/Amphibian, motif 20; Nudi, Xenopus/Amphibian, motif 20; DCP2; NUDT20

SUPPLIER INFO

ABBIOTEC

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