Reactivities: | Human, Mouse |
Presku: | AAP52246 |
Size: | 100ug |
Weight: | 72kDa |
Gene: | 27214 |
Format: | Lyophilized powder |
Target: | Dbf4 is a regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role DNA in replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle. |
Alternative names: | AA545217; Ask |