DA, Xenopus/Amphibian,, Xenopus/Amphibian, (7A11) Antibody

DA, Xenopus/Amphibian,, Xenopus/Amphibian, (Death-domain associated protein) is a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. DA, Xenopus/Amphibian,, Xenopus/Amphibian, interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus DA, Xenopus/Amphibian,, Xenopus/Amphibian, is a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, DA, Xenopus/Amphibian,, Xenopus/Amphibian, may regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation,Porcinehosphorylation and polyubiquitination.

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SPECIFICATIONS

Catalog Number

252921

Size

0.1 ml

Applications

FC, IF

Reactivities

Hum

Format

Each vial contains 0.1 ml IgG in PBS pH7.4, 50% glycerol with 0.03% sodium azide. Antibody was purified by Protein-G affinity chromatography.

P Type

Mouse Monoclonal Antibody

Antigen

Purified recombinant fragment of human DA, Xenopus/Amphibian,, Xenopus/Amphibian, e, Xenopus/Amphibian,pressed in E. coli.

Isotype

Mouse IgG1

Accession

Q9UER7

Clonality

7A11

Additional Info

Death domain-associated protein 6; Da, Xenopus/Amphibian,, Xenopus/Amphibian,; hDa, Xenopus/Amphibian,, Xenopus/Amphibian,; ETS1-associated protein 1; EAP1; Fas death domain-associated protein; BING2; DAP6; DA, Xenopus/Amphibian,, Xenopus/Amphibian,