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Cytokeratin-1 Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 251612

Cytokeratin-1 Antibody

Cytokeratin-1 regulates the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein kinase C (RACK1/GNB2L1). Defects in KRT1 are a cause of bullous congenital ichthyosiform erythroderma, also known as epidermolytic hyperkeratosis (EHK) or bullous erythroderma ichthyosiformis congenita of Brocq. BCIE is an autosomal dominant skin disorder characterized by widespread blistering and an ichthyotic erythroderma at birth that persists into adulthood

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SPECIFICATIONS

Catalog Number

251612

Size

0.1 mg

Applications

IHC

Reactivities

Hum, Mouse, Rabbit

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

P Type

Rabbit Polyclonal Antibody

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human cytokeratin-1.

Isotype

Rabbit Ig

Accession

P04264; P05787; P08727

Additional Info

Cytokeratin-1; Cytokeratin-8; Cytokeratin-19; Keratin, type II cytoskeletal 1; CK-1; Keratin-1; K1; 67 kDa cytokeratin; Type-II keratin Kb1; Hair alpha protein; KRT1; KRTA; CK-8; Cytokeratin-8; Keratin, type II cytoskeletal 8; CK-8; Keratin-8; K8; KRT8; CYK8; Keratin, type I cytoskeletal 19; Cytokeratin-19; CK-19; Keratin-19; K19; KRT19

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