logo
logo
Cytidine aminohydrolase Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 252010

Cytidine aminohydrolase Antibody

Activation-induced cytidine deaminase (cytidine aminohydrolase) is an RNA-editing deaminase involved in somatic hypermutation, gene conversion, and class-switch recombination. Cytidine deaminase is required for several crucial steps of B-cell terminal differentiation necessary for efficient antibody responses. Defects in cytidine deaminase are the cause of hyper-IgM immunodeficiency syndrome type 2 (HIGM2) also known as hyper-IgM syndrome 2. HIGM2 is an autosomal recessive disorder characterized by normal or elevated serum IgM levels with absence of IgG, IgA, and IgE, resulting in a profound susceptibility to bacterial infections. HIGM2 causes the absence of Ig class switch recombination (CSR), the lack of Ig somatic hypermutations, and lymph node hyperplasia caused by the presence of giant germinal centers.

Prices direct from ABBIOTEC

Quick response times

Exclusive Absave savings/discounts

SPECIFICATIONS

Catalog Number

252010

Size

0.1 mg

Applications

WB

Reactivities

Hum

Format

Each vial contains 0.1 mL of crude serum with 0.09% sodium azide.

P Type

Rabbit Polyclonal Antibody

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human cytidine aminohydrolase.\n

Isotype

Rabbit Ig

Accession

Q9GZ, Xenopus/Amphibian,7

Additional Info

Cytidine aminohydrolase; Activation-induced cytidine deaminase; AICDA; AID

SUPPLIER INFO

ABBIOTEC

Latest promotions

New brilliant antibodies, and new lower prices!For flow cytometry reagents in general, \"bright is better.\" The violet-excitable BD Horizon™ BV421 and...

Buy any polyclonal or monoclonal antibody from our extensive range of pre-made antibodies and for a limited time only receive a $50 discount!(T&C apply:...

We're so sure that you'll prefer Cayman Assay kits over your present brand that we're willing to give you a free assay kit to prove it!

For the past decade scientists have extensively used ATS secondary toxin conjugates to make their own targeted toxins for in vitro use.The ability to combine...

10% Discount on 2 Rabbit Polyclonal Antibody Service. With over 20 years experience, SDIX has developed into the premier US custom antibody producer,...

Did your supplier increase the price of Fetal Bovine Serum? Did they substitute the US Origin with USDA? Well say no more! Innovative Research is still...

Bulk Cytokines with Custom Vialing.20 - 50% off cytokines, growth factors, chemokines and more...For a limited time Cell Sciences is offering substantial...

Are you planning to have a customised antibody made for your research?Since 2000, Everest has been producing a catalog containing thousands of affinity...