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CYP3A4 (cytochrome P450, family 3, subfamily A, polypeptide 4) Blocking Peptide (the middle region of CYP3A4)(100ug)

CYP3A4 (cytochrome P450, family 3, subfamily A, polypeptide 4) Blocking Peptide (the middle region of CYP3A4)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-CYP3A4 Antibody(ARP51348_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP51348
Size: 100ug
Weight: 57kDa
Gene: 1576
Format: Lyophilized powder
Target: This gene, CYP3A4, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs which are are used today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist; however, it is now thought that this sequence represents a transcript variant of CYP3A4.
Alternative names: CP33; CP34; CYP3A; CYP3A3; HLP; MGC126680; NF-25; P450C3; P450PCN1
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