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CYP21A2 (cytochrome P450, family 21, subfamily A, polypeptide 2) Blocking Peptide (the C terminal of CYP21A2)(100ug)

CYP21A2 (cytochrome P450, family 21, subfamily A, polypeptide 2) Blocking Peptide (the C terminal of CYP21A2)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-CYP21A2 Antibody (ARP60144_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP60144
Size: 100ug
Weight: 56kDa
Gene: 1589
Format: Lyophilized powder
Target: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates steroids at the 21 position. Its activity is required for the synthesis of steroid hormones including cortisol and aldosterone. Mutations in this gene cause congenital adrenal hyperplasia. A related pseudogene is located near this gene; gene conversion events involving the functional gene and the pseudogene are thought to account for many cases of steroid 21-hydroxylase deficiency. Two transcript variants encoding different isoforms have been found for this gene.
Alternative names: CA21H; CAH1; CPS1; CYP21; CYP21B; MGC150536; MGC150537; P450c21B
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