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CYFIP1 (cytoplasmic FMR1 interacting protein 1 ) Blocking Peptide (the C terminal of CYFIP1)(100ug)

CYFIP1 (cytoplasmic FMR1 interacting protein 1 ) Blocking Peptide (the C terminal of CYFIP1)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-CYFIP1 Antibody (ARP64537_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP64537
Size: 100ug
Weight: 145kDa
Gene: 23191
Format: Lyophilized powder
Target: CYFIP1 is a component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit is an adapter between EIF4E and FMR1. CYFIP1 promotes the translation repression activity of FMR1 in brain probably by mediating its association with EIF4E and mRNA By similarity. CYFIP1 regulates formation of membrane ruffles and lamellipodia. CYFIP1 plays a role in axon outgrowth. CYFIP1 binds to F-actin but not to RNA. Part of the WAVE complex that regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1. Regulator of epithelial morphogenesis. CYFIP1 may act as an invasion suppressor in cancers.
Alternative names: FLJ45151; P140SRA-1; SHYC; SRA1
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