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Cyclin D2 Antibody

Cyclin D2 Antibody

Cat no: 251517

Supplier: ABBIOTEC
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Cyclin D2 is the regulatory component of the cyclin D2-CDK4 (DC) comple, Xenopus/Amphibian, that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G1/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F comple, Xenopus/Amphibian, and the subsequent transcription of E2F target genes which are responsible for the progression through the G1 phase. Cyclin D-CDK4 comple, Xenopus/Amphibian,es are major integrators of various mitogenenic and antimitogenic signals.
Catalogue number: 251517
Reactivities: Human, Mouse, Porcine, Rabbit
Applications: Immunohistochemistry
Size: 0.1 mg
Accession: P30279
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human cyclin D2.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type: Rabbit Polyclonal Antibody
Isotype: Rabbit Ig
Additional info: Cyclin D2; G1/S-specific cyclin-D2; CCND2
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