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Cyclin D1 Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 250491

Cyclin D1 Antibody

Cyclin-D1 (BCL-1) comple, Xenopus/Amphibian,es with CDK4 and CDK6 serine/threonine protein kinases to impart substrate specificity. Cyclin-D1 is essential for G1/S phase transition. Following DNA damage, Cyclin-D1 is phosphorylated at Thr-286 by MAP kinases, leading to its FB, Xenopus/Amphibian,O31-mediated ubiquitination and subsequent degradation. Chromosomal aberrations of CCND1 lead to various neoplastic and proliferative disorders.

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SPECIFICATIONS

Catalog Number

250491

Size

0.1 mg

Applications

IHC

Reactivities

Hum, Mouse, Rabbit

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

P Type

Rabbit Polyclonal Antibody

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the central region of rodent Cyclin-D1.

Isotype

Rabbit Ig

Accession

P25322

Additional Info

Cyclin D1; G1/S-specific cyclin-D1; PRAD1 oncogene; BCL-1 oncogene; BCL1; PRAD1; B-cell lymphoma 1 protein; CCND1; Cyl-1

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