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Cyclin D1 Antibody

Cyclin D1 Antibody

Cat no: 250491

Supplier: ABBIOTEC
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Cyclin-D1 (BCL-1) comple, Xenopus/Amphibian,es with CDK4 and CDK6 serine/threonine protein kinases to impart substrate specificity. Cyclin-D1 is essential for G1/S phase transition. Following DNA damage, Cyclin-D1 is phosphorylated at Thr-286 by MAP kinases, leading to its FB, Xenopus/Amphibian,O31-mediated ubiquitination and subsequent degradation. Chromosomal aberrations of CCND1 lead to various neoplastic and proliferative disorders.
Catalogue number: 250491
Reactivities: Human, Mouse, Rabbit
Applications: Immunohistochemistry
Size: 0.1 mg
Accession: P25322
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the central region of rodent Cyclin-D1.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type: Rabbit Polyclonal Antibody
Isotype: Rabbit Ig
Additional info: Cyclin D1; G1/S-specific cyclin-D1; PRAD1 oncogene; BCL-1 oncogene; BCL1; PRAD1; B-cell lymphoma 1 protein; CCND1; Cyl-1
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