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CX3CL1 Antibody (OAPB00058)

CX3CL1 Antibody (OAPB00058)

Chemokines are a family of proteins associated with the trafficking of leukocytes in immune surveillance and inflammatory cell recruitment. They are classified based on the positions of key cysteine residues. CX3CL1 is a CX3C chemokine known to induce adhesion and migration of leukocytes mediated by a membrane-bound and soluble form respectively. Recent experiments have shown that CX3CL1 can suppress the production of nitrous oxide, interleukin-6, and TNF-alpha in activated microglia and neuronal cells, suggesting that it may act as an intrinsic inhibitor against neurotoxicity by activated microglia. Its receptor, CX3CR1, also functions as a co-receptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by CX3CL1. CX3CL1 is ofen observed migrating at 80

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SPECIFICATIONS

Size

0.1 mg

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum, Mouse

Presku

OAPB00058

Target

CX3CR1 ligand

Alternative Names

CX3CL1; CX3C; CX3C membrane-anchored chemokine; neurotactin; small

SUPPLIER INFO

Aviva Systems Biology Incorporated

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