Reactivities: | Human, Mouse |
Presku: | AAP62057 |
Size: | 100ug |
Weight: | 111kDa |
Gene: | 72584 |
Format: | Lyophilized powder |
Target: | Cul4b is a core component of multiple cullin-RING-based E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition subunit. CUL4B may act within the complex as a scaffold protein, contributing to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. |
Alternative names: | 2700050M05Rik; AA409770; KIAA0695; mKIAA0695 |