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CTNNB1 (catenin (cadherin-associated protein), beta 1, 88kDa ) Blocking Peptide (the C terminal of CTNNB1)(100ug)

CTNNB1 (catenin (cadherin-associated protein), beta 1, 88kDa ) Blocking Peptide (the C terminal of CTNNB1)(100ug)

This is a synthetic peptide designed for use in combination with anti-CTNNB1 Antibody (P100601_T100), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.

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SPECIFICATIONS

Size

100ug

Reactivities

Hum

Format

Lyophilized powder

Presku

AAP30904

Target

The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene.

Weight

85kDa

Gene Id

1499

Alternative Names

CTNNB; DKFZp686D02253; FLJ25606; FLJ37923

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