Reactivities: | Human, Mouse |
Presku: | AAP46746 |
Size: | 100ug |
Weight: | 123kDa |
Gene: | 53419 |
Format: | Lyophilized powder |
Target: | Corin is a Serine-type endopeptidase involved in atrial natriuretic peptide hormone (NPPA) processing. It converts through proteolytic cleavage the non-functional propeptide NPPA into the active hormone, thereby regulating blood pressure in heart and promoting natriuresis, diuresis and vasodilation. Proteolytic cleavage of pro-NPPA also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Corin also acts as a regulator of sodium reabsorption in kidney. May also process pro-NPPB the B-type natriuretic peptide. |
Alternative names: | AV273130; Lrp4 |