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COQ6 (coenzyme Q6 homolog, monooxygenase (S. cerevisiae) ) Blocking Peptide (the N terminal of COQ6)(100ug)

COQ6 (coenzyme Q6 homolog, monooxygenase (S. cerevisiae) ) Blocking Peptide (the N terminal of COQ6)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-COQ6 Antibody (ARP64161_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP64161
Size: 100ug
Weight: 48kDa
Gene: 51004
Format: Lyophilized powder
Target: The protein encoded by this gene belongs to the ubiH/COQ6 family. It is an evolutionarily conserved monooxygenase required for the biosynthesis of coenzyme Q10 (or ubiquinone), which is an essential component of the mitochondrial electron transport chain, and one of the most potent lipophilic antioxidants implicated in the protection of cell damage by reactive oxygen species. Knockdown of this gene in mouse and zebrafish results in decreased growth due to increased apoptosis. Mutations in this gene are associated with autosomal recessive coenzyme Q10 deficiency-6 (COQ10D6), which manifests as nephrotic syndrome with sensorineural deafness. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Alternative names: CGI10; COQ10D6
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