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Collagen IV (Mouse) Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 250485

Collagen IV (Mouse) Antibody

Type IV collagen is the major structural component of glomerular basement membranes forming a "chicken-wire" meshwork together with laminins,Porcineroteoglycans and entactin/nidogen. There are si, Xenopus/Amphibian, type IV collagen isoforms, alpha 1(IV)-alpha 6(IV), each of which can form a triple heli, Xenopus/Amphibian, structure with 2 other chains to generate type IV collagen network. Defects in type IV collagen are a cause of Alport syndrome autosomal recessive (APSAR), characterized by glomerulonephritis, renal failure, sensorineural deafness and eye abnormalities. Defects in type IV collagen are also a cause of benign familial hematuria (BFH). The antibody is directed against rodent alpha 1 isoform.

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SPECIFICATIONS

Catalog Number

250485

Size

0.1 mg

Applications

IHC

Reactivities

Prc, Rabbit

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

P Type

Rabbit Polyclonal Antibody

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the center region of mouse type IV collagen (isoform alpha 1).

Isotype

Rabbit Ig

Accession

Q9QZR9

Additional Info

Collagen alpha-4(IV) chain; COL4A4

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