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COL6A2 (Human) cDNA (1ug)

COL6A2 (Human) cDNA (1ug)

Supplier: Aviva Systems Biology Incorporated
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The ORF of human COL6A2 is amplified by PCR using a high fidelity enzyme and sub-cloned into a Prokaryotic expression vector under the control of the tac promoter. The expression of the gene has been confirmed by Western blot using an anti-COL6A2 polyclonal antibody.
Presku: ANA11171
Size: 1ug
Gene: 1292
Target: This gene encodes one of the three alpha chains of type VI collagen, a beaded filament collagen found in most connective tissues. The product of this gene contains several domains similar to von Willebrand Factor type A domains. These domains have been shown to bind extracellular matrix proteins, an interaction that explains the importance of this collagen in organizing matrix components. Mutations in this gene are associated with Bethlem myopathy and Ullrich scleroatonic muscular dystrophy. Three transcript variants have been identified for this gene.
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