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COL4A3 (collagen, type IV, alpha 3 (Goodpasture antigen)) Blocking Peptide (the N terminal of COL4A3)(100ug)

COL4A3 (collagen, type IV, alpha 3 (Goodpasture antigen)) Blocking Peptide (the N terminal of COL4A3)(100ug)

This is a synthetic peptide designed for use in combination with anti-COL4A3 Antibody (ARP60007_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.

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SPECIFICATIONS

Size

100ug

Reactivities

Hum

Format

Lyophilized powder

Presku

AAP60007

Target

This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.

Weight

137kDa

Gene Id

1277

Alternative Names

OI4

SUPPLIER INFO

Aviva Systems Biology Incorporated

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