
Supplier:
Aviva Systems Biology IncorporatedCMA1 (chymase 1, mast cell) Blocking Peptide (the C terminal of CMA1)(100ug)
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SPECIFICATIONS
Size
100ug
Reactivities
Hum
Format
Lyophilized powder
Presku
AAP59991
Target
CMA1 is a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Angiotensin II has been implicated in blood pressure control and in the pathogenesis of hypertension, cardiac hypertrophy, and heart failure. Thus, this gene product is a target for cardiovascular disease therapies.
Weight
27kDa
Gene Id
1215
Alternative Names
CYH; MCT1; MGC119890; MGC119891; chymase
Applications
ELISA, WB
Hosts
Mouse
Applications
IHC
Hosts
Mouse
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