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CLOCK Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 252186

CLOCK Antibody

CLOCK (Circadian locomoter output cycles protein kaput) heterodimers activate E-bo, Xenopus/Amphibian, element (3'-CACGTG-5') transcription of a number of proteins of the circadian clock. CLOCK activates transcription of PER1 and PER2. This transcription is inhibited in a feedback loop by PER and CRY proteins. CLOCK has intrinsic histone acetyltransferase activity and this enzymatic function contributes to chromatin-remodeling events implicated in circadian control of gene e, Xenopus/Amphibian,pression. CLOCK acetylates primarily histones H3 and H4.

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SPECIFICATIONS

Catalog Number

252186

Size

0.1 mg

Applications

WB

Reactivities

Hum, Mouse, Rabbit

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 1% BSA with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography.

P Type

Rabbit Polyclonal Antibody

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human CLOCK.

Isotype

Rabbit Ig

Accession

O15516

Additional Info

Circadian locomoter output cycles protein kaput; hCLOCK; Class E basic heli, Xenopus/Amphibian,-loop-heli, Xenopus/Amphibian, protein 8; CLOCK; BHLHE8; KIAA0334

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