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CLOCK (8F7) Antibody

CLOCK (8F7) Antibody

Cat no: 252994

Supplier: ABBIOTEC
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CLOCK (Circadian locomoter output cycles protein kaput) heterodimers activate E-bo, Xenopus/Amphibian, element (3'-CACGTG-5') transcription of a number of proteins of the circadian clock. CLOCK activates transcription of PER1 and PER2. This transcription is inhibited in a feedback loop by PER and CRY proteins. CLOCK has intrinsic histone acetyltransferase activity and this enzymatic function contributes to chromatin-remodeling events implicated in circadian control of gene e, Xenopus/Amphibian,pression. CLOCK acetylates primarily histones H3 and H4.
Catalogue number: 252994
Reactivities: Human
Applications: Flow Cytometry
Size: 0.1 ml
Accession: O15516
Antigen: Purified recombinant fragment of human CLOCK e, Xenopus/Amphibian,pressed in E. coli.

Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
P type: Mouse Monoclonal Antibody
Isotype: Mouse IgG1
Clonality: 8F7
Additional info: Circadian locomoter output cycles protein kaput; hCLOCK; Class E basic heli, Xenopus/Amphibian,-loop-heli, Xenopus/Amphibian, protein 8; CLOCK; BHLHE8; KIAA0334
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