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Clk4 (CDC like kinase 4 ) Blocking Peptide (the N terminal of Clk4)(100ug)

Clk4 (CDC like kinase 4 ) Blocking Peptide (the N terminal of Clk4)(100ug)


Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-Clk4 Antibody (ARP30646_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human, Mouse
Presku: AAP30646
Size: 100ug
Weight: 57kDa
Gene: 12750
Format: Lyophilized powder
Target: Clk4 is a dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Clk4 phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Clk4 phosphorylates SRSF1 and SRSF3. Clk4 is required for the regulation of alternative splicing of MAPT/TAU. Clk4 regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells.
Alternative names: AI987988; C85119