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CLDN9 (Human) cDNA (1ug)

CLDN9 (Human) cDNA (1ug)

Supplier: Aviva Systems Biology Incorporated
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The ORF of human CLDN9 is amplified by PCR using a high fidelity enzyme and sub-cloned into a Prokaryotic expression vector under the control of the tac promoter. The expression of the gene has been confirmed by Western blot using an anti-CLDN9 polyclonal antibody.
Presku: ANA11409
Size: 1ug
Gene: 9080
Target: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This protein is one of the entry cofactors for hepatitis C virus. Mouse studies revealed that this gene is required for the preservation of sensory cells in the hearing organ and the gene deficiency is associated with deafness.
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