Supplier:
Aviva Systems Biology IncorporatedChst2 (carbohydrate sulfotransferase 2 ) Blocking Peptide (the middle region of Chst2)(100ug)
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SPECIFICATIONS
Size
100ug
Reactivities
Mouse
Format
Lyophilized powder
Presku
AAP46422
Target
Chst2 catalyzes the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues within keratan-like structures on N-linked glycans and within mucin-associated glycans that can ultimately serve as L-selectin ligands. L-selectin ligands are present in high endothelial cells (HEVs) and play a central role in lymphocyte homing at sites of inflammation. Chst2 participates in biosynthesis of L-selectin ligand sialyl 6-sulfo Lewis X and in lymphocyte homing to Peyer patches. It has no activity toward O-linked sugars. Its substrate specificity may be influenced by its subcellular location. It sulfates GlcNAc residues at terminal, non-reducing ends of oligosaccharide chains.
Weight
58kDa
Gene Id
The peptide is characterized by mass spectroscopy
Alternative Names
AI428561; AW121776; C130041E03Rik; Chts2; GST-2; GlcNAc6ST; Gn6st
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