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CHRNA4 Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 251410

CHRNA4 Antibody

After binding acetylcholine, the neuronal acetylcholine receptor (CHRNA4) responds by an e, Xenopus/Amphibian,tensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Defects in CHRNA4 are the cause of nocturnal frontal lobe epilepsy type 1 (ENFL1), also symbolized ADNFLE. ENFL1 is an autosomal dominant epilepsy characterized by nocturnal seizures with hyperkinetic automatisms and poorly organized stereotyped movements.

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SPECIFICATIONS

Catalog Number

251410

Size

0.1 mg

Applications

IHC

Reactivities

Hum, Mouse, Rabbit

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

P Type

Rabbit Polyclonal Antibody

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human CHRNA4.

Isotype

Rabbit Ig

Accession

P43681

Additional Info

N-AChR alpha 4; Nicotinic acetylcholine receptor alpha 4; Neuronal acetylcholine receptor subunit alpha-4; NACRA4; Neuronal nicotinic acetylcholine receptor alpha 4; CHRNA4

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