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Chmp2b (charged multivesicular body protein 2B ) Blocking Peptide (the N terminal of Chmp2b)(100ug)

Chmp2b (charged multivesicular body protein 2B ) Blocking Peptide (the N terminal of Chmp2b)(100ug)

This is a synthetic peptide designed for use in combination with anti-Chmp2b Antibody (ARP54967_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.

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SPECIFICATIONS

Size

100ug

Reactivities

Hum, Rat

Format

Lyophilized powder

Presku

AAP54967

Target

Chmp2b is involved in late steps of the endosomal multivesicular bodies (MVB) pathway. Chmp2b recognizes membrane-associated ESCRT-III assemblies and catalyzes their disassembly, possibly in combination with membrane fission. Chmp2b redistributes the ESCRT-III components to the cytoplasm for further rounds of MVB sorting. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. In conjunction with the ESCRT machinery Chmp2b also appears to function in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis. Involved in cytokinesis .

Weight

23kDa

Gene Id

363720

Alternative Names

RGD1306781

SUPPLIER INFO

Aviva Systems Biology Incorporated

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