Calcitonin gene-related peptide is a 37 amino-acid vasoactive neuropeptide (MW 3789) widely e, Xenopus/Amphibian,pressed throughout the central and peripheral nervous system. CGRP has potent vasodilatory effects probably serving as a regulator of regional blood flow, in addition to a variety of other cellular effects. This antibody binds an epitope within the aa 19-37 of human alpha-CGRP. Based on inhibition ELISA, this antibody cross-reacts up to 12% with human beta-CGRP and human amylin, whereas there is weak cross-reaction (<4%) with rat alpha-CGRP.