Supplier:
Aviva Systems Biology IncorporatedCDKN2C Protein Lysate (GST tagged) (Expressed in bacteria) (200ug)
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SPECIFICATIONS
Size
200ug
Presku
APL10264
Target
The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode an identical protein, have been reported.
Weight
38
Gene Id
1031
Alternative Names
p18; INK4C; p18-INK4C
SUPPLIER INFO
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