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CDKN2B (cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)) Blocking Peptide (100ug)

CDKN2B (cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)) Blocking Peptide (100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-CDKN2B antibody (Catalogue #: AVARP03047_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Presku: AAP30194
Size: 100 ug
Weight: 15kDa
Gene: 1030
Format: Lyophilized powder
Target: CDKN2B's gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. CDKN2B is a cyclin-dependent kinase inhibitor, which forms a complex with CDK4 or CDK6, and prevents the activation of the CDK kinases, thus the encoded protein functions as a cell growth regulator that controls cell cycle G1 progression. The expression of this gene was found to be dramatically induced by TGF beta, which suggested its role in the TGF beta induced growth inhibition.
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