Supplier:
Aviva Systems Biology IncorporatedCDK2AP1 (cyclin-dependent kinase 2 associated protein 1 ) Blocking Peptide (the C terminal of CDK2AP1)(100ug)
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SPECIFICATIONS
Size
100ug
Reactivities
Hum
Format
Lyophilized powder
Presku
AAP64230
Target
The protein encoded by this gene is a specific CDK2-associated protein, which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggested the regulatory role in DNA replication during S phase of the cell cycle. A similar gene in hamster was isolated from, and functions as a growth suppressor of normal keratinocytes.
Weight
12kDa
Gene Id
8099
Alternative Names
DOC1; DORC1; ST19; doc-1; p12DOC-1
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