Supplier:
Aviva Systems Biology IncorporatedCdk14 (cyclin-dependent kinase 14 ) Blocking Peptide (the C terminal of Cdk14)(100ug)
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SPECIFICATIONS
Size
100ug
Reactivities
Hum, Mouse
Format
Lyophilized powder
Presku
AAP61958
Target
Cdk14 is a Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin. Cdk14 acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by mediating the phosphorylation of LRP6 at 'Ser-1490', leading to the activation of the Wnt signaling pathway. Cdk14 acts as a regulator of cell cycle progression and cell proliferation via its interaction with CCDN3. Phosphorylates RB1 in vitro, however the relevance of such result remains to be confirmed in vivo. Cdk14 may also play a role in meiosis, neuron differentiation and may indirectly act as a negative regulator of insulin-responsive glucose transport.
Weight
53kDa
Gene Id
18647
Alternative Names
Pftk1; mKIAA0834
SUPPLIER INFO
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