Reactivities: | Human |
Presku: | AAP45174 |
Size: | 100ug |
Weight: | 82kDa |
Gene: | 1002 |
Format: | Lyophilized powder |
Target: | CDH4 gene is a classical cadherin from the cadherin superfamily. The protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization. |
Alternative names: | CAD4; FLJ22202; FLJ40547; MGC126700; MGC138355; RCAD |