Reactivities: | Human |
Presku: | AAP63640 |
Size: | 100ug |
Weight: | 58kDa |
Gene: | 79577 |
Format: | Lyophilized powder |
Target: | This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma. |
Alternative names: | C1orf28; FLJ23316; HPTJT; HRPT2; HYX |